A mural of Red Wing with a steamship, houses, and a bridge.

Find hotels in Southeast Minnesota, MN from CA $97

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 16 - Aug 17
Tomorrow
Aug 17 - Aug 18
Next weekend
Aug 21 - Aug 23
In two weeks
Aug 28 - Aug 30

Filter by

Star rating

Guest rating

Our top choices for Southeast Minnesota hotels

Spa
Hotel
Hot tub
Breakfast included
Bed & breakfast

1. Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
Rochester
United States
Albert
CA $135
CA $156 total
includes taxes & fees
Aug 30 - Aug 31
Hampton Inn & Suites Rochester-North

2. Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
Rochester
United States
Anne
CA $107
CA $124 total
includes taxes & fees
Aug 23 - Aug 24
Comfort Inn & Suites Rochester South Mayo Clinic

3. Comfort Inn & Suites West - Medical Center

Comfort Inn & Suites West - Medical Center
Rochester
United States
Gary
CA $121
CA $139 total
includes taxes & fees
Sep 5 - Sep 6
Comfort Inn & Suites West - Medical Center

4. Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
Rochester
United States
Stephanie
CA $128
CA $147 total
includes taxes & fees
Aug 21 - Aug 22
Holiday Inn Express Rochester South - Mayo Area by IHG

5. Spark by Hilton Rochester South

Spark by Hilton Rochester South
Rochester
United States
Lijing
CA $113
CA $130 total
includes taxes & fees
Aug 23 - Aug 24
Spark by Hilton Rochester South

6. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Downtown Rochester
United States
Misty
CA $143
CA $165 total
includes taxes & fees
Aug 21 - Aug 22
Hotel Indigo Rochester – Mayo Clinic Area by IHG

7. TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
Kutzky Park
United States
Jorge
CA $170
CA $196 total
includes taxes & fees
Aug 21 - Aug 22
TownePlace Suites by Marriott Rochester Mayo Clinic Area

8. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Rochester
United States
Margita
CA $130
CA $150 total
includes taxes & fees
Aug 23 - Aug 24
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

9. Treasure Island Resort & Casino

Treasure Island Resort & Casino
Welch
United States
Julie
CA $96
CA $122 total
includes taxes & fees
Sep 9 - Sep 10
Treasure Island Resort & Casino

10. Coratel Inn & Suites by Jasper Owatonna

Coratel Inn & Suites by Jasper Owatonna
Owatonna
United States
Fallon
CA $111
CA $123 total
includes taxes & fees
Aug 24 - Aug 25
Coratel Inn & Suites by Jasper Owatonna

11. Hampton Inn Rochester-South

Hampton Inn Rochester-South
Rochester
United States
Lynne
CA $130
CA $149 total
includes taxes & fees
Aug 28 - Aug 29
Hampton Inn Rochester-South

12. EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
Kutzky Park
United States
paul
CA $139
CA $178 total
includes taxes & fees
Aug 28 - Aug 29
EVEN Hotel Rochester - Mayo Clinic Area by IHG

13. Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
Rochester
United States
Richard
CA $176
CA $202 total
includes taxes & fees
Sep 5 - Sep 6
Residence Inn by Marriott Rochester Mayo Clinic Area South

14. Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Kutzky Park
United States
Janet
CA $132
CA $152 total
includes taxes & fees
Aug 22 - Aug 23
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

15. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
Rochester
United States
Markus
CA $98
CA $112 total
includes taxes & fees
Sep 13 - Sep 14
Econo Lodge Mayo Clinic Area

16. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Historic Southwest
United States
Brandolyn
CA $158
CA $182 total
includes taxes & fees
Aug 21 - Aug 22
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

17. Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
Downtown Rochester
United States
Jennifer
CA $238
CA $274 total
includes taxes & fees
Aug 22 - Aug 23
Hilton Rochester Mayo Clinic Area

18. Staybridge Suites Rochester - Commerce Dr NW by IHG

Staybridge Suites Rochester - Commerce Dr NW by IHG
Rochester
United States
Brittney
CA $176
CA $203 total
includes taxes & fees
Aug 22 - Aug 23
Staybridge Suites Rochester - Commerce Dr NW by IHG

19. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Rochester
United States
Darrel
CA $105
CA $121 total
includes taxes & fees
Aug 23 - Aug 24
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

20. Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center
Rochester
United States
Robert M
CA $119
CA $137 total
includes taxes & fees
Sep 13 - Sep 14
Sleep Inn & Suites West-Near Medical Center
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southeast Minnesota attractions

A waterfall cascading over a rocky cliff.
Photo by Linda Strub

Niagara Cave

9.2/10 (23 reviews)
Commune with nature and explore the great outdoors at Niagara Cave during your travels in Harmony. Amble within the natural setting or visit the churches in this family-friendly area.
See properties
A cave with a reflective pool and illuminated walls.
Photo by T. Jen

Forestville Mystery Cave State Park

9.0/10 (22 reviews)
Commune with nature and explore the great outdoors at Forestville Mystery Cave State Park during your travels in Preston. Wander the parks or discover the area's countryside.
See properties

Mayo Civic Center

9.2/10 (818 reviews)
Catch an event at Mayo Civic Center during your trip to Rochester. Attend a sporting event or simply visit the area's shops.
See properties

Apache Mall

8.6/10 (1,101 reviews)
During your visit to Rochester, you can do some window-shopping at Apache Mall. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
See properties

Rochester Recreation Center

8.0/10 (205 reviews)
Catch an event at Rochester Recreation Center during your trip to Rochester. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
See properties

Olmsted County Fairgrounds

7.8/10 (177 reviews)
Take the family on an outing to Olmsted County Fairgrounds during your trip to Rochester. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
See properties

Shattuck-St. Mary's School

9.6/10 (69 reviews)
Enjoy the collegiate vibe when you visit Shattuck-St. Mary's School, during your trip to Faribault. Visit the shops in this family-friendly area, or simply enjoy its coffeehouses.
See properties

Learn more about Southeast Minnesota

Explore the family-friendly area of Southeast Minnesota—restaurants, sports teams, and sights from Mayowood Mansion to Cascade Lake Beach.

See all hotels in Southeast Minnesota
A lake surrounded by dense forest and a distant hill with a fort.

Top Southeast Minnesota Hotel Reviews

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

10/10 Excellent
"We loved this property! The pool was fun for every age. It was very nice to have the bedroom with full bath plus another half bath in the living room area."
JOY 2-night trip
Posted 4 hours ago
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

10/10 Excellent
"We had an issue with our first room battery was dead on door lock so they were able to move us. We appreciated the accomadati9n and the breakfast. Staff was helpful. Could use maybe a swing or slide outside by the dinosaur statue. My son pived it."
Zackary 3-night trip
Posted 8 hours ago
Med City Inn & Suites - Mayo Clinic Area
Hampton Inn Rochester-South

Hampton Inn Rochester-South

10/10 Excellent
"Everything functioned as it should."
William 1-night trip
Posted 13 hours ago
Hampton Inn Rochester-South
Kahler Grand Hotel

Kahler Grand Hotel

10/10 Excellent
"The location could not be better."
Kevin 1-night trip
Posted 13 hours ago
Kahler Grand Hotel
Brentwood Inn & Suites

Brentwood Inn & Suites

8/10 Good
"I find the Brentwood a very good place to stay when I am visiting the Mayo Clinic. My room is always ready when I arrive in town and the staff helpful. The room is clean and adequate for I want for my one-night stay. I particularly like the free or included parking fee and best of all the connection to the subway directly from the hotel. The price point is attractive for the accommodations."
Charlotte 1-night trip
Posted 1 day ago
Brentwood Inn & Suites
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

10/10 Excellent
"The shuttle to Mayo and St Mary's was super convenient and reliable."
carol 3-night trip
Posted 1 day ago
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

8/10 Good
"Office staff, particularly Affinity, wss extremely helpful! Major drawback was parking was oversold which seriously inconvenience guests who went out for dinner."
Kalvin 6-night trip
Posted 6 days ago
Staybridge Suites Rochester - Mayo Clinic Area by IHG

More cheap stays in Southeast Minnesota

Super 8 by Wyndham Winona MN

Super 8 by Wyndham Winona MN

1025 Sugar Loaf Rd Winona MN
CA $86
CA $98 total
Sep 13 - Sep 14
includes taxes & fees
7.6/10 Good! (1,017 reviews)
Super 8 by Wyndham Winona MN
Days Inn by Wyndham Austin

Days Inn by Wyndham Austin

700 16th Ave Nw Austin MN
CA $100
CA $111 total
Aug 30 - Aug 31
includes taxes & fees
8/10 Very good! (809 reviews)
Days Inn by Wyndham Austin
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN
CA $105
CA $121 total
Aug 18 - Aug 19
includes taxes & fees
8/10 Very good! (1,005 reviews)
Med City Inn & Suites - Mayo Clinic Area
Hampton Inn Rochester-South

Hampton Inn Rochester-South

1755 S Broadway Rochester MN
CA $130
CA $149 total
Aug 28 - Aug 29
includes taxes & fees
9/10 Wonderful! (1,004 reviews)
Hampton Inn Rochester-South
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

1517 16th St Sw Rochester MN
CA $130
CA $150 total
Aug 23 - Aug 24
includes taxes & fees
8.2/10 Very good! (1,004 reviews)
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Brentwood Inn & Suites

Brentwood Inn & Suites

123 Fourth Ave. NW Rochester MN
CA $173
CA $200 total
Aug 18 - Aug 19
includes taxes & fees
8.8/10 Excellent! (1,006 reviews)
Brentwood Inn & Suites

Hotels in Southeast Minnesota with star rating

Explore a world of travel with Expedia